Compile Data Set for Download or QSAR
Found 230 from Sichuan University and Collaborative Innovation Center
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM172038(US10155002, Compound 44 | US10647700, Compound EPZ...)copy SMILEScopy InChI
Affinity DataIC50: 0.340nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7M50PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of FGR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CSK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JJDPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China.

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China.

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant human EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate incubate for 15 mins by LANCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human YES using biotinyl-beta Abeta-Abeta AYQAEENTYDEYEN as substrate incubate for 30 mins by LANCE assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544770(CHEMBL4646490)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544756(CHEMBL4637350)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512005(CHEMBL4440181)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China.

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of Her2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7M50PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China.

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of ErBB2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JJDPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))TBA
LigandPNGBDBM50511997(CHEMBL4525187)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant LYN using biotinyl-beta amyloid beta amyloid beta AKVEKIGEGTYGVVYK as substrate measured after 120 mins in the presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China.

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD measured after 15 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human JAK3 using Ulight-CAGAGAIETDKEYYTVKD as substrate incubate for 60 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant JAK3 using Ulight-CAGAGAIETDKEYYTVKD measured after 60 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544755(CHEMBL4645357)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50028142(CHEMBL2177300)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JJDPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, PR China.

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant HER2 using biotinyl-beta amyloid beta amyloid beta AAEEEEYFELVAKKK measured after 10 mins in the presence of ATP by H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544755(CHEMBL4645357)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type EZH2 (unknown origin) in presence of 1 uM SAM by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544762(CHEMBL4633751)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544772(CHEMBL4646766)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JJDPubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))TBA
LigandPNGBDBM50511997(CHEMBL4525187)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant FGR using Ulight-TK peptide as substrate measured after 60 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))TBA
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of FRK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544764(CHEMBL4647553)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant LCK using Ulight-Poly GAT[EAY(1:1:1) as substrate measured after 10 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512009(CHEMBL4544821)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50260597(CHEMBL4079901)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JJDPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JJDPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human LCK using Ulight-Poly GAT[EAY(1:1:1)]n as substrate incubate for 10 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272TRPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544769(CHEMBL4638443)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))TBA
LigandPNGBDBM50511997(CHEMBL4525187)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80BXPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50579920(CHEMBL5071797)copy SMILES
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant full length FAK incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V99PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50579918(CHEMBL5078868)copy SMILES
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant full length FAK incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V99PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50544779(CHEMBL4645331)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P644QPubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))TBA
LigandPNGBDBM50269615(CHEMBL4095253)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged BMX expressed in Sf21 cells preincubated for 5 mins followed by biotinyl-beta Abet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7M50PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant full length FAK incubated for 40 mins in presence of Mg/ATP mix by [gamma p33]-ATP based scintillation counting metho...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM19151((1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propa...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JJDPubMed
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